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- /*
- * nvbio
- * Copyright (c) 2011-2014, NVIDIA CORPORATION. All rights reserved.
- *
- * Redistribution and use in source and binary forms, with or without
- * modification, are permitted provided that the following conditions are met:
- * * Redistributions of source code must retain the above copyright
- * notice, this list of conditions and the following disclaimer.
- * * Redistributions in binary form must reproduce the above copyright
- * notice, this list of conditions and the following disclaimer in the
- * documentation and/or other materials provided with the distribution.
- * * Neither the name of the NVIDIA CORPORATION nor the
- * names of its contributors may be used to endorse or promote products
- * derived from this software without specific prior written permission.
- *
- * THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS "AS IS" AND
- * ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED
- * WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE
- * DISCLAIMED. IN NO EVENT SHALL NVIDIA CORPORATION BE LIABLE FOR ANY
- * DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL DAMAGES
- * (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR SERVICES;
- * LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER CAUSED AND
- * ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY, OR TORT
- * (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE OF THIS
- * SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
- */
- // alignment.h
- //
- #pragma once
- #include <stdio.h>
- #include <stdlib.h>
- #include <nvbio/alignment/alignment.h>
- #include <nvbio/alignment/batched.h>
- #include <nvbio/strings/string_set.h>
- #include <nvbio/io/sequence/sequence.h>
- using namespace nvbio;
- // a functor to extract the read infixes from the hit diagonals
- //
- struct read_infixes
- {
- // constructor
- NVBIO_HOST_DEVICE
- read_infixes(const io::ConstSequenceDataView reads) :
- m_reads( reads ) {}
- // functor operator
- NVBIO_HOST_DEVICE
- string_infix_coord_type operator() (const uint2 diagonal) const
- {
- const io::SequenceDataAccess<DNA_N> reads( m_reads );
- const uint32 read_id = diagonal.y;
- // fetch the read range
- return reads.get_range( read_id );
- }
- const io::ConstSequenceDataView m_reads;
- };
- // a functor to extract the genome infixes from the hit diagonals
- //
- template <uint32 BAND_LEN>
- struct genome_infixes
- {
- // constructor
- NVBIO_HOST_DEVICE
- genome_infixes(const uint32 genome_len, const io::ConstSequenceDataView reads) :
- m_genome_len( genome_len ),
- m_reads( reads ) {}
- // functor operator
- NVBIO_HOST_DEVICE
- string_infix_coord_type operator() (const uint2 diagonal) const
- {
- const io::SequenceDataAccess<DNA_N> reads( m_reads );
- const uint32 read_id = diagonal.y;
- const uint32 text_pos = diagonal.x;
- // fetch the read range
- const uint2 read_range = reads.get_range( read_id );
- const uint32 read_len = read_range.y - read_range.x;
- // compute the segment of text to align to
- const uint32 genome_begin = text_pos > BAND_LEN/2 ? text_pos - BAND_LEN/2 : 0u;
- const uint32 genome_end = nvbio::min( genome_begin + read_len + BAND_LEN, m_genome_len );
- return make_uint2( genome_begin, genome_end );
- }
- const uint32 m_genome_len;
- const io::ConstSequenceDataView m_reads;
- };
- // a functor to extract the score from a sink
- //
- struct sink_score
- {
- typedef aln::BestSink<int16> argument_type;
- typedef int16 result_type;
- // functor operator
- NVBIO_HOST_DEVICE
- int16 operator() (const aln::BestSink<int16>& sink) const { return sink.score; }
- };
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