assembly.h 2.5 KB

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  1. /*
  2. * nvbio
  3. * Copyright (c) 2011-2014, NVIDIA CORPORATION. All rights reserved.
  4. *
  5. * Redistribution and use in source and binary forms, with or without
  6. * modification, are permitted provided that the following conditions are met:
  7. * * Redistributions of source code must retain the above copyright
  8. * notice, this list of conditions and the following disclaimer.
  9. * * Redistributions in binary form must reproduce the above copyright
  10. * notice, this list of conditions and the following disclaimer in the
  11. * documentation and/or other materials provided with the distribution.
  12. * * Neither the name of the NVIDIA CORPORATION nor the
  13. * names of its contributors may be used to endorse or promote products
  14. * derived from this software without specific prior written permission.
  15. *
  16. * THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS "AS IS" AND
  17. * ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED
  18. * WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE
  19. * DISCLAIMED. IN NO EVENT SHALL NVIDIA CORPORATION BE LIABLE FOR ANY
  20. * DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL DAMAGES
  21. * (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR SERVICES;
  22. * LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER CAUSED AND
  23. * ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY, OR TORT
  24. * (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE OF THIS
  25. * SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
  26. */
  27. #pragma once
  28. #include <nvbio/basic/types.h>
  29. #include <nvbio/basic/vector.h>
  30. #include <nvbio/basic/packed_vector.h>
  31. #include "haplotype_caller.h"
  32. #include "assembly_types.h"
  33. using namespace nvbio;
  34. void local_assembly(assembly_pipeline* pipeline)
  35. {
  36. // [read correction]
  37. // create assembly graphs for given kmer size(s)
  38. debruijn_graph assembly_graph;
  39. assembly_graph.construct_graph(
  40. pipeline->d_seq_set,
  41. pipeline->d_active_region_ids,
  42. pipeline->kmer_size,
  43. false);
  44. printf("Constructed assembly graph for kmer size %u with %u nodes and %u edges \n",
  45. pipeline->kmer_size, assembly_graph.n_nodes, assembly_graph.n_edges);
  46. //assembly_graph.print_dot_graph(pipeline->d_seq_set);
  47. // check complexity
  48. // assembly_graph.topological_sort();
  49. // check for cycles
  50. // post-process: pruning, dangling chain recovery...
  51. // find best paths
  52. //assembly_graph.find_k_best_paths(pipeline->k_best_haplotypes);
  53. }