se_analyzer.h 3.0 KB

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  1. /*
  2. * nvbio
  3. * Copyright (c) 2011-2014, NVIDIA CORPORATION. All rights reserved.
  4. *
  5. * Redistribution and use in source and binary forms, with or without
  6. * modification, are permitted provided that the following conditions are met:
  7. * * Redistributions of source code must retain the above copyright
  8. * notice, this list of conditions and the following disclaimer.
  9. * * Redistributions in binary form must reproduce the above copyright
  10. * notice, this list of conditions and the following disclaimer in the
  11. * documentation and/or other materials provided with the distribution.
  12. * * Neither the name of the NVIDIA CORPORATION nor the
  13. * names of its contributors may be used to endorse or promote products
  14. * derived from this software without specific prior written permission.
  15. *
  16. * THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS "AS IS" AND
  17. * ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED
  18. * WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE
  19. * DISCLAIMED. IN NO EVENT SHALL NVIDIA CORPORATION BE LIABLE FOR ANY
  20. * DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL DAMAGES
  21. * (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR SERVICES;
  22. * LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER CAUSED AND
  23. * ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY, OR TORT
  24. * (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE OF THIS
  25. * SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
  26. */
  27. #pragma once
  28. #include <nvbio-aln-diff/stats.h>
  29. #include <nvbio-aln-diff/alignment.h>
  30. #include <nvbio-aln-diff/filter.h>
  31. namespace nvbio {
  32. namespace alndiff {
  33. struct SEAnalyzer
  34. {
  35. SEAnalyzer(Filter& filter);
  36. void push(
  37. const Alignment& aln1,
  38. const Alignment& aln2);
  39. void generate_report(const char* aln_file_name1, const char* aln_file_name2, const char* report);
  40. // flush any open files
  41. //
  42. void flush() { m_filter.flush(); }
  43. float mismatched() const { return float(n_mismatched)/float(n + n_mismatched); }
  44. float different_ref() const { return float(n_different_ref.count)/float(n); }
  45. float distant() const { return float(n_distant.count)/float(n); }
  46. float discordant() const { return float(n_discordant.count)/float(n); }
  47. uint32 filtered() const { return m_filter.filtered(); }
  48. Filter& m_filter;
  49. BooleanStats mapped;
  50. BooleanStats unique;
  51. BooleanStats ambiguous;
  52. BooleanStats not_ambiguous;
  53. Histogram<8> mapped_L_not_R_by_mapQ;
  54. Histogram<8> mapped_R_not_L_by_mapQ;
  55. Histogram<8> unique_L_not_R_by_mapQ;
  56. Histogram<8> unique_R_not_L_by_mapQ;
  57. Histogram<8> ambiguous_L_not_R_by_mapQ;
  58. Histogram<8> ambiguous_R_not_L_by_mapQ;
  59. uint32 n;
  60. uint32 n_mismatched;
  61. Histogram<8> n_different_ref;
  62. Histogram<8> n_distant;
  63. Histogram<8> n_discordant;
  64. AlignmentStats al_stats;
  65. AlignmentStats distant_stats;
  66. AlignmentStats discordant_stats;
  67. };
  68. } // namespace alndiff
  69. } // namespace nvbio