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- /*
- * nvbio
- * Copyright (c) 2011-2014, NVIDIA CORPORATION. All rights reserved.
- *
- * Redistribution and use in source and binary forms, with or without
- * modification, are permitted provided that the following conditions are met:
- * * Redistributions of source code must retain the above copyright
- * notice, this list of conditions and the following disclaimer.
- * * Redistributions in binary form must reproduce the above copyright
- * notice, this list of conditions and the following disclaimer in the
- * documentation and/or other materials provided with the distribution.
- * * Neither the name of the NVIDIA CORPORATION nor the
- * names of its contributors may be used to endorse or promote products
- * derived from this software without specific prior written permission.
- *
- * THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS "AS IS" AND
- * ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED
- * WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE
- * DISCLAIMED. IN NO EVENT SHALL NVIDIA CORPORATION BE LIABLE FOR ANY
- * DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL DAMAGES
- * (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR SERVICES;
- * LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER CAUSED AND
- * ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY, OR TORT
- * (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE OF THIS
- * SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
- */
- ///
- ///\file mapping.h
- ///
- #pragma once
- #include <nvBowtie/bowtie2/cuda/defs.h>
- #include <nvBowtie/bowtie2/cuda/utils.h>
- #include <nvBowtie/bowtie2/cuda/params.h>
- #include <nvBowtie/bowtie2/cuda/seed_hit.h>
- #include <nvBowtie/bowtie2/cuda/seed_hit_deque_array.h>
- #include <nvBowtie/bowtie2/cuda/reads_def.h>
- #include <nvBowtie/bowtie2/cuda/fmindex_def.h>
- #include <nvbio/io/utils.h>
- #include <nvbio/basic/cuda/pingpong_queues.h>
- #include <nvbio/basic/cached_iterator.h>
- #include <nvbio/basic/packedstream.h>
- #include <nvbio/basic/priority_deque.h>
- #include <nvbio/basic/strided_iterator.h>
- #include <nvbio/basic/algorithms.h>
- namespace nvbio {
- namespace bowtie2 {
- namespace cuda {
- ///@addtogroup nvBowtie
- ///@{
- /// \defgroup Mapping
- ///
- /// The functions in this module implement the very first pipeline stage: seed mapping.
- /// In this stage each read is broken up into many short, possibly overlapping seeds
- /// which get mapped against the reference genome using an FM-index.
- /// The output is a vector of variable-lenth "priority deques", one for each read,
- /// containing the set of Suffix Array ranges (\ref SeedHits) where the seeds align,
- /// prioritized by the inverse of the range size (see \ref SeedHitDequeArray).
- ///
- /// The module implements many mapping algorithms:
- ///
- /// - exact: allowing exact matches only
- /// - approx-hybrid: allowing 0 mismatches in a subseed of the seed, and up to 1 mismatch in the rest
- /// - approx-case-pruning: allowing 1 mismatch across the entire seed, using 2 FM-indices to perform
- /// the search with case pruning (i.e. searching an alignment with 0 mismatches in the first half of
- /// the seed in the forward FM-index, and an alignment with 0 mismatches in the second half in the
- /// reverse FM-index).
- ///
- ///@addtogroup Mapping
- ///@{
- ///
- /// For all the seed hit ranges, output the range size in out_ranges.
- ///
- void gather_ranges(
- const uint32 count,
- const uint32 n_reads,
- SeedHitDequeArrayDeviceView hits,
- const uint32* hit_counts_scan,
- uint64* out_ranges);
- ///
- /// perform exact read mapping
- ///
- void map_whole_read(
- const ReadsDef::type& read_batch,
- const FMIndexDef::type fmi,
- const FMIndexDef::type rfmi,
- const nvbio::cuda::PingPongQueuesView<uint32> queues,
- uint8* reseed,
- SeedHitDequeArrayDeviceView hits,
- const ParamsPOD params,
- const bool fw,
- const bool rc);
- ///
- /// perform one run of exact seed mapping for all the reads in the input queue,
- /// writing reads that need another run in the output queue
- ///
- void map_exact(
- const ReadsDef::type& read_batch,
- const FMIndexDef::type fmi,
- const FMIndexDef::type rfmi,
- const uint32 retry,
- const nvbio::cuda::PingPongQueuesView<uint32> queues,
- uint8* reseed,
- SeedHitDequeArrayDeviceView hits,
- const ParamsPOD params,
- const bool fw,
- const bool rc);
- ///
- /// perform multiple runs of exact seed mapping in one go and keep the best
- ///
- void map_exact(
- const ReadsDef::type& read_batch,
- const FMIndexDef::type fmi,
- const FMIndexDef::type rfmi,
- SeedHitDequeArrayDeviceView hits,
- const uint2 seed_range,
- const ParamsPOD params,
- const bool fw,
- const bool rc);
- ///
- /// perform one run of approximate seed mapping for all the reads in the input queue,
- /// writing reads that need another run in the output queue
- ///
- void map_approx(
- const ReadsDef::type& read_batch,
- const FMIndexDef::type fmi,
- const FMIndexDef::type rfmi,
- const uint32 retry,
- const nvbio::cuda::PingPongQueuesView<uint32> queues,
- uint8* reseed,
- SeedHitDequeArrayDeviceView hits,
- const ParamsPOD params,
- const bool fw,
- const bool rc);
- ///
- /// perform multiple runs of approximate seed mapping in one go and keep the best
- ///
- void map_approx(
- const ReadsDef::type& read_batch,
- const FMIndexDef::type fmi,
- const FMIndexDef::type rfmi,
- SeedHitDequeArrayDeviceView hits,
- const uint2 seed_range,
- const ParamsPOD params,
- const bool fw,
- const bool rc);
- ///
- /// perform one run of seed mapping
- ///
- void map(
- const ReadsDef::type& read_batch,
- const FMIndexDef::type fmi,
- const FMIndexDef::type rfmi,
- const uint32 retry,
- const nvbio::cuda::PingPongQueuesView<uint32> queues,
- uint8* reseed,
- SeedHitDequeArrayDeviceView hits,
- const ParamsPOD params,
- const bool fw,
- const bool rc);
- ///@} // group Mapping
- ///@} // group nvBowtie
- } // namespace cuda
- } // namespace bowtie2
- } // namespace nvbio
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