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- /*
- * nvbio
- * Copyright (c) 2011-2014, NVIDIA CORPORATION. All rights reserved.
- *
- * Redistribution and use in source and binary forms, with or without
- * modification, are permitted provided that the following conditions are met:
- * * Redistributions of source code must retain the above copyright
- * notice, this list of conditions and the following disclaimer.
- * * Redistributions in binary form must reproduce the above copyright
- * notice, this list of conditions and the following disclaimer in the
- * documentation and/or other materials provided with the distribution.
- * * Neither the name of the NVIDIA CORPORATION nor the
- * names of its contributors may be used to endorse or promote products
- * derived from this software without specific prior written permission.
- *
- * THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS "AS IS" AND
- * ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED
- * WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE
- * DISCLAIMED. IN NO EVENT SHALL NVIDIA CORPORATION BE LIABLE FOR ANY
- * DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL DAMAGES
- * (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR SERVICES;
- * LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER CAUSED AND
- * ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY, OR TORT
- * (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE OF THIS
- * SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
- */
- #pragma once
- #include <nvBowtie/bowtie2/cuda/defs.h>
- #include <nvBowtie/bowtie2/cuda/params.h>
- #include <nvbio/basic/timer.h>
- #include <vector>
- #include <deque>
- namespace nvbio { namespace io { struct BestAlignments; } }
- namespace nvbio {
- namespace bowtie2 {
- namespace cuda {
- typedef nvbio::TimeSeries KernelStats;
- struct AlignmentStats
- {
- AlignmentStats()
- : n_mapped(0),
- n_ambiguous(0),
- n_unambiguous(0),
- n_unique(0),
- n_multiple(0),
- mapped_ed_histogram(4096, 0),
- mapped_ed_histogram_fwd(4096, 0),
- mapped_ed_histogram_rev(4096, 0),
- mapped_log_ed_histogram(12, 0)
- {
- for(uint32 c = 0; c < 64; c++)
- mapq_bins[c] = 0;
- for(uint32 c = 0; c < 8; c++)
- mapq_log_bins[c] = 0;
- for(uint32 c = 0; c < 64; c++)
- for(uint32 d = 0; d < 64; d++)
- mapped_ed_correlation[c][d] = 0;
- }
- // mapping quality stats
- uint64 mapq_bins[64];
- uint64 mapq_log_bins[8];
- // mapping stats
- uint32 n_mapped; // number of mapped reads
- uint32 n_ambiguous; // number of reads mapped to more than one place with the same score
- uint32 n_unambiguous; // number of reads with a single best score (even if mapped to multiple locations)
- uint32 n_unique; // number of reads mapped to a single location
- uint32 n_multiple; // number of reads mapped to more than one location
- // edit distance scoring histograms
- std::vector<uint32> mapped_ed_histogram; // aggregate histogram of edit-distance scores per read
- std::vector<uint32> mapped_ed_histogram_fwd; // histogram of edit-distance scores for reads mapped to the forward sequence
- std::vector<uint32> mapped_ed_histogram_rev; // histogram of edit-distance scores for reads mapped to the reverse-complemented sequence
- std::vector<uint32> mapped_log_ed_histogram; // aggregate histogram of log edit-distance scores per read
- std::vector<uint32> mapped_log_mapq_histogram; // aggregate histogram of log mapq scores per read
- // edit distance correlation (xxxnsubtil: what exactly does this measure?)
- uint32 mapped_ed_correlation[64][64];
- // merge stats
- void merge(const AlignmentStats& stats)
- {
- n_mapped += stats.n_mapped;
- n_ambiguous += stats.n_ambiguous;
- n_unambiguous += stats.n_unambiguous;
- n_unique += stats.n_unique;
- n_multiple += stats.n_multiple;
- for (uint32 i = 0; i < mapped_ed_histogram.size(); ++i)
- {
- mapped_ed_histogram[i] += stats.mapped_ed_histogram[i];
- mapped_ed_histogram_fwd[i] += stats.mapped_ed_histogram_fwd[i];
- mapped_ed_histogram_rev[i] += stats.mapped_ed_histogram_rev[i];
- }
- for (uint32 i = 0; i < 12; ++i)
- mapped_log_ed_histogram[i] += stats.mapped_log_ed_histogram[i];
- for(uint32 c = 0; c < 64; c++)
- mapq_bins[c] += stats.mapq_bins[c];
- for(uint32 c = 0; c < 8; c++)
- mapq_log_bins[c] += stats.mapq_log_bins[c];
- for(uint32 c = 0; c < 64; c++)
- for(uint32 d = 0; d < 64; d++)
- mapped_ed_correlation[c][d] += stats.mapped_ed_correlation[c][d];
- }
- };
- //
- // Global statistics
- //
- struct Stats
- {
- // constructor
- Stats(const Params _params = Params());
- // timing stats
- float global_time;
- KernelStats map;
- KernelStats select;
- KernelStats sort;
- KernelStats locate;
- KernelStats score;
- KernelStats opposite_score;
- KernelStats backtrack;
- KernelStats backtrack_opposite;
- KernelStats finalize;
- KernelStats alignments_DtoH;
- KernelStats read_HtoD;
- KernelStats read_io;
- KernelStats io;
- KernelStats scoring_pipe;
- // detailed mapping stats
- AlignmentStats concordant;
- AlignmentStats discordant;
- AlignmentStats mate1;
- AlignmentStats mate2;
- // mapping stats
- uint32 n_reads;
- // extensive (seeding) stats
- uint64 hits_total;
- uint64 hits_ranges;
- uint32 hits_max;
- uint32 hits_max_range;
- uint64 hits_top_total;
- uint32 hits_top_max;
- uint64 hits_bins[28];
- uint64 hits_top_bins[28];
- uint32 hits_stats;
- Params params;
- void track_alignment_statistics(
- const io::BestAlignments& alignment1,
- const io::BestAlignments& alignment2,
- const uint8 mapq);
- void track_alignment_statistics(
- AlignmentStats* mate,
- const io::BestAlignments& alignment,
- const uint8 mapq);
- };
- void generate_report_header(const uint32 n_reads, const Params& params, AlignmentStats& aln_stats, const uint32 n_devices, const Stats* device_stats, const char* report);
- void generate_device_report(const uint32 id, Stats& stats, AlignmentStats& aln_stats, const char* report);
- } // namespace cuda
- } // namespace bowtie2
- } // namespace nvbio
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